| | U-boat 65 | 1988 | Nuova Bell Games | uboat65 | | 0.00 |
 | U.N. Defense Force: Earth Joker | 1993 | Visco | earthjkr | Shooter / Flying Vertical | 7.14 |
 | U.N. Squadron (USA) | 1989 | Capcom / Daipro | unsquad | Shooter / Flying Horizontal | 8.10 |
 | U.S. Championship V'ball (bootleg of Japan set) (clone of: vball) | 1988 | bootleg | vball2pjb | | 0.00 |
| U.S. Championship V'ball (bootleg of US set) (clone of: vball) | 1988 | bootleg | vballb | | 0.00 |
| U.S. Championship V'ball (Japan) (clone of: vball) | 1988 | Technos Japan | vball2pj | Sports / Volleyball | 0.00 |
| U.S. Championship V'ball (US) | 1988 | Technos Japan | vball | Sports / Volleyball | 7.60 |
 | U.S. Classic | 1989 | Seta | usclssic | Sports / Golf | 7.50 |
 | U.S. Navy (Japan 901012) (clone of: cawing) | 1990 | Capcom | cawingj | Shooter / Flying Horizontal | 0.00 |
| | U.S.A. Football | 1993 | Alvin G | usafootb | | 0.00 |
| | Uchuu Daisakusen: Chocovader Contactee (Japan, CVC1 Ver.A) | 2002 | Namco | chocovdr | | 0.00 |
| | Uchuu Tokkyuu Medalian | 1997 | Sigma | ucytokyu | | 0.00 |
 | Ufo Robo Dangar (12/1/1986) | 1986 | Nichibutsu | dangar | Shooter / Flying Vertical | 5.22 |
| Ufo Robo Dangar (9/26/1986) (clone of: dangar) | 1986 | Nichibutsu | dangar2 | Shooter / Flying Vertical | 0.00 |
| Ufo Robo Dangar (bootleg) (clone of: dangar) | 1986 | bootleg | dangarb | Shooter / Flying Vertical | 0.00 |
 | Ufo Senshi Yohko Chan (MC-8123, 317-0064) | 1988 | Sega | ufosensi | Maze / Shooter Large | 6.00 |
| Ufo Senshi Yohko Chan (not encrypted) (clone of: ufosensi) | 1988 | bootleg | ufosensib | | 0.00 |
| | UFO-X | 1984 | Playmatic | ufo_x | | 0.00 |
| | Ultimate (Bellfruit) (Scorpion 1) | 1969 | BFM | sc1ult | | 0.00 |
| | Ultimate Arctic Thunder (clone of: arctthnd) | 2001 | Midway Games | arctthndult | | 0.00 |
